Oishi K, Zilles K, Amunts K, Faria A, Jiang H, Li X, Akhter K, Hua K, Woods R, Toga AW, Pike GB, Rosa-Neto P, Evans A, Zhang J, Huang H, Miller MI, van Zijl PC, Mazziotta J, Mori S.
Russell H. Morgan Department of Radiology and Radiological Science, The
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Abtract: Structural delineation and assignment are the fundamental steps in
understanding the anatomy of the human brain. The white matter has been
structurally defined in the past only at its core regions (deep white
matter). However, the most peripheral white matter areas, which are
interleaved between the cortex and the deep white matter, have lacked
clear anatomical definitions and parcellations. We used axonal fiber
alignment information from diffusion tensor imaging (DTI) to delineate
the peripheral white matter, and investigated its relationship with the
cortex and the deep white matter. Using DTI data from 81 healthy
subjects, we identified nine common, blade-like anatomical regions,
which were further parcellated into 21 subregions based on the cortical
anatomy. Four short association fiber tracts connecting adjacent gyri
(U-fibers) were also identified reproducibly among the healthy
population. We anticipate that this atlas will be useful resource for
atlas-based white matter anatomical studies.
Full access to text in Neuroimage. 2008 Jul 18.