CALIO, P. L., SIMOES, M. J., MORA, O. A. et al.
Abstract : The authors performed an ultrastructural investigation in order to study whether the estrogen would be able to modify the answer of the gingival stroma of rats. The results showed that the lamina propria of the gingiva of animals in permanent oestrous and oophorectomy treated with estrogens was rich in cells with predominance of collagen fibers. It was also observed a great number of eosinophils and active fibroblasts, few macrophages and lymphocytes. Some electrontranslucent spaces were observed in the stroma. In group of oophorectomyzed, the cellular stroma showed a great amount of amorphous and fibrilar ground substance, atrophic fibroblasts, some macrophages and few leukocytes showing degenerative features. The gingival stroma was atrophic in the group treated with dexamethasone, showing a great number of cells and collagen fibers as wells as fibroblasts and fibrocytes. Reduced number of macrophages, plasmocytes and leukocytes was observed. It was possible to conclude that the gingival stroma of rats should be considered a target organ of estrogen and that oophorectomy does not modify this feature
Keywords: Gingiva; Electron microscopy; Estrogen; Dexamethasone
Rev. chil. anat., 1997, vol.15, no.1, p.93-97. Full text available in Spanish.