Molecular Biotechnology: Principles and Applications of Recombinant DNA
Completely revised and updated, this second edition of the best-selling Molecular Biotechnology covers both the underlying scientific principles and the wide-ranging industrial, agricultural, pharmaceutical, and biomedical applications of recombinant DNA technology. This new edition includes expanded coverage of the types of organisms and cells used in molecular biotechnology, DNA, RNA, and protein synthesis, the methodology and applications of genetic engineering of plants, and microbial production of therapeutic agents. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. TABLE OF CONTENTS: Fundamentals of Molecular Biotechnology The Molecular Biotechnology Revolution Molecular Biotechnology Biological Systems DNA, RNA, and Protein Synthesis Recombinant DNA Technology Chemical Synthesis, Sequencing, and Amplification of DNA Manipulation of Gene Expression in Prokaryotes Recombinant Protein Production in Eukaryotic Cells Directed Mutagenesis and Protein Engineering Molecular Biotechnology of Microbial Systems Molecular Diagnostics Microbial Production of Therapeutic Agents Vaccines Synthesis of Commercial Products by Recombinant Microorganisms Bioremediation and Biomass Utilization Plant Growth-Promoting Bacteria Microbial Insecticides Large-Scale Production of Proteins from Recombinant Microorganisms Eukaryotic Systems Genetic Engineering of Plants: Methodology Genetic Engineering of Plants: Applications Transgenic Animals Human Molecular Genetics Human Gene Therapy Regulating and Patenting Molecular Biotechnology Regulating the Use of Biotechnology Patenting Biotechnology Inventions –This text refers to an out of print or unavailable edition of this title.
Univ. of Waterloo, Ontario, Canada. Introductory textbook explains what biotechnology is as a scientific discipline, how research in the area is conducted, and how this technology may impact our future. Includes new information on cloning, and gene therapy. For students in biotechnology and genetic engineering. Previous edition: c1998.
Good overview but lacks technical rigor, April 6, 2000
I am currently using this book for a course in Molecular Biotechnology taught through the chemistry department. Although the book covers a wide range of biotechnology fields, from manipulation of gene expression in prokaryotes and eukaryotes through human gene therapy, it does so in a somewhat shallow and repetitive way. I have also seen clearer and more concise diagrams covering similar topics in other biochemistry books, and there is a paucity of in-depth coverage in any particular area. This is not necessarily the authors’s fault, however, arising from the plethora of information found in the biotechnology field. If someone wants a broad review of molecular biotechnology, this is a decent book, but if you want to focus on a specific area within biotechnology, look somewhere else.