1. The reciprocal succession of things in time or place; the act of following and being followed by turns; alternate succession, performance, or occurrence; as, the alternation of day and night, cold and heat, summer and winter, hope and fear.
2. (Science: mathematics) permutation.
3. The response of the congregation speaking alternately with the minister. Alternation of generation. See generation.
Origin: L. Alternatio: cf. F. Alternation.