Dictionary > Androstenediol

Androstenediol

Definition
noun, plural: androstenediols
A steroid hormone, with a chemical formula of C19H30O2, and a precursor of androgen and estrogen
Supplement
Androgen is one of the major classes of sex steroids (or sex hormones) of vertebrates, including humans. Androgens include androstenediol (A5), androstenedione (A4), dehydroepiandrosterone (DHEA), dihydrotestosterone (DHT), androsterone, and testosterone. Androstenediol (A5) is an unsaturated, weak endogenous androgen. It contains two alcohol groups. Three isomers of androstenediol occur. A5 is closely related to androstenedione (A4) in terms of structure. A5, though, is less androgenic than A4. A5 is a derivative of androstane and an intermediate in testosterone biosynthesis (from dehydroepiandrosterone). It also has estrogenic activity just at other androgens, such as DHEA and A4.
A5 may also be synthesized synthetically. It is one of the anabolic steroids. It is administered orally. It has been found to have an effect in the immune system. It can stimulate the production of white blood cells and platelets. As such, it has been studied for use as a radiation countermeasure, and is being investigated for the treatment of acute radiation syndrome.1
Chemical formula:

  • C19H30O2

Synonym(s):

  • hermaphrodiol
  • 5-androstenediol (A5)
  • androst-5-ene-3β,17β-diol
  • See also:

    Reference(s):

    1 Whitnall, M. H., Elliott, T. B., Harding, R. A., Inal, C. E., Landauer, M. R., Wilhelmsen, C. L., McKinney, L., Miner, V. L., Jackson, W. E. 3rd, Loria, R. M., Ledney, G. D., & Seed, T. M. (2000). “Androstenediol stimulates myelopoiesis and enhances resistance to infection in gamma-irradiated mice”. Int. J. Immunopharmacol. 22 (1): 1–14. doi:10.1016/s0192-0561(99)00059-4.


    You will also like...

    Chemical effects on plant growth and development
    Effect of Chemicals on Growth & Development in Organisms

    Plants and animals need elements, such as nitrogen, phosphorus, potassium, and magnesium for proper growth and developme..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

    Homeostatic Mechanisms and Cellular Communication
    Homeostatic Mechanisms and Cellular Communication

    Homeostasis is the relatively stable conditions of the internal environment that result from compensatory regulatory res..

    complete-dominance
    Dominance

    This tutorial presents Gregor Mendel's law of dominance. Learn more about this form of inheritance and how it can be pre..

    Early Mammals on Earth
    Early Mammals on Earth

    The Earth's ecosphere was rapidly changing and throwing up a wide range of ecological niches that new adaptive organisms..

    DNA carries genes coding for proteins
    Genetic Information and Protein Synthesis

    Genes are expressed through the process of protein synthesis. This elaborate tutorial provides an in-depth review of the..