Anisocoria is a condition characterized by the benign inequality of the size of the pupils of the eyes, changing from one hour to the next. It is fairly common, affecting 20% of the population whose pupil size difference is typically less than 1 mm. In this regard, it is referred to as simple anisocoria (also called physiological anisocoria). Anisocoria can be a harmless condition or it may be a symptom of a medical condition (e.g. Horner’s syndrome, Adie’s syndrome, migraines). Synonyms: essential anisocoria, physiologic anisocoria, simple-central anisocoria.
- Lam, B. L., Thompson, H.S., & Corbett, J. J. (Jul 15, 1987). “The prevalence of simple anisocoria”. American Journal of Ophthalmology. 104 (1): 69–73.
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