Dictionary > Atropine


(Science: drug) a toxic alkaloid extracted from belladonna and other members of thenightshade family, it is typically used to dilate the eye and to stopmuscular spasms.
pharmacologic action: Parasympatholytic. Competitive blockade of acetylcholine at muscarinic receptors. Increases sinus node automaticity and av conduction.
Uses: treat bradycardia, asystole, and av block
Dose: 0.5 – 1.0 mg for bradycardia every 3 – 5 min to a total dose of 0.04 mg/kg. Doses smaller than 0.5 mg can cause a paradoxical bradycardia due to sympathomimetic effects Typically 3 mg is adequate to completely block vagal effects atropine is well absorbed via endotracheal route – administer 1-2 mg diluted in 10 ml sterile water or normal saline.
potential complications: 1. Tachyarrhythmias 2. Exacerbation of myocardial ischemia 3. Low dose may cause paradoxical bradycardia 4. Dry mouth, urinary retention, flushed and hot skin 5. Crosses blood-brain barrier which can cause delirium
Note: The denervated heart will not respond to atropine.

You will also like...

Sigmund Freud and Carl Gustav Jung
Sigmund Freud and Carl Gustav Jung

In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

genes controlling growth and development
Control of Growth & Development

Control of Growth & Development tutorials look at how the genetic makeup determines the biological processes on a da..

Schematic diagram of bacterial lactose operon
Gene Action – Operon Hypothesis

This tutorial focuses on the way genes control and determine every aspect of the body. It describes lac operon as an exa..

Cambial cells
Plant Tissues

Plant organs are comprised of tissues working together for a common function. The different types of plant tissues are m..

Early Earth
The Origins of Life

This tutorial digs into the past to investigate the origins of life. The section is split into geological periods in the..


Stems primarily provide plants structural support. This tutorial includes lectures on the external form of a woody twig ..