Dictionary > Bordetella pertussis

Bordetella pertussis

A non-motile coccobacillus gram-negative organism that emerged singly or in pairs associated with whooping cough in human.
Bordetella pertussis contains filamentous hemoagglutinin that is nutritionally fastidious which able to invade tissues and become pathogenic in humans. It is the bacterium responsible for whooping cough in human causing high mortality rate in infants. It also generates various substances with toxic activity like endotoxins and exotoxins.
Bordetella pertussis colonizes the cilia of mammalian respiratory epithelium which used several toxins to bind and destroy the epithelial cells. Its mode of infection is through utilizing hemoagglutinin that aids the bacteria in binding to the cilia surface then releasing pertussis toxin an exotoxin which able to enters the cell and activates the production of cAMP, finally it releases the tracheal cytotoxin causes the destruction of the cilia in the epithelial cells.
Bordetella pertussis has the ability to infect the function of host immune system which inhibits the G protein coupling resulted in phagocytes that converts too much ATP to cyclic AMP causing disturbances in cellular signaling mechanisms as well as preventing phagocytes from correctly responding to an infection.
Scientific classification:
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Beta Proteobacteria
Order: Burkholderiales
Family: Alcaligenaceae
Genus: Bordetella
Species: Bordetella pertussis
See also:
Whooping cough

You will also like...

Pikas are an indicator species for climate change
Indicator Species and Endangered Species

Certain species are capable of expressing characteristics indicative of the state of the ecosystem they occupy. They are..

Adaptive Radiation
Adaptive Radiation

The diversification of several new species from a recent ancestral source, each adapted to utilize or occupy a vacant ad..

Chemical effects on plant growth and development
Effect of Chemicals on Growth & Development in Organisms

Plants and animals need elements, such as nitrogen, phosphorus, potassium, and magnesium for proper growth and developme..

Buttress roots

This study guide tackles plant roots in greater detail. It delves into the development of plant roots, the root structur..

Pink Lotus plant on a pond
Freshwater Lentic Communities & Animals

This tutorial looks at some of the communities in freshwater lentic habitats. For instance, symbiosis occurs in a commun..

The process of photosynthesis
Photosynthesis – Photolysis and Carbon Fixation

Photosynthesis is the process that plants undertake to create organic materials from carbon dioxide and water, with the ..