Dictionary > Chromosome 14

Chromosome 14

Definition
noun
In humans, the autosome that spans about 107 million base pairs, likely to contain about 600 or less than 900 genes, and is an acrocentric chromosome
Supplement
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 14 is an acrocentric autosome. It spans almost 107 million base pairs (i.e. about 3 to 3.5 % of the total DNA). It is likely to contain about 600 or less than 900 genes. Some of the genes found on chromosome 14 are CRIP2 (coding for cysteine-rich protein 2), GPHB5 (for glycoprotein hormone beta-5), VASH1 (for vasohibin-1), and TSHR (for thyroid stimulating hormone receptor).
Some of the diseases and disorders related to the genes on chromosome 14 include Alzheimer disease, Burkitt’s lymphoma, congenital hypothyroidism, Krabbe disease, mosaic monosomy 14, multiple myeloma, and Niemann-Pick disease.
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