Dictionary > Chromosome 15

Chromosome 15

Definition
noun
In humans, the autosome that spans about 101 million base pairs, likely containing about 600 to 700 genes, and is an acrocentric chromosome
Supplement
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 15 is an acrocentric autosome. It spans almost 101 million base pairs (i.e. about 3 to 3.5 % of the total DNA). IT is likely to have 600 to 700 genes. Some of the genes are CHSY1 (coding for chondroitin sulfate synthase 1), human leukocyte antigen gene (for β2-microglobulin), CHSY1 (for chondroitin sulfate synthase 1), SENP8 (for sentrin-specific protease 8), SPN1 (for Snurportin1), and VPS39 (for hVam6p/Vps39-like protein).
Some of the diseases and disorders related to the genes on chromosome 15 include Angelman syndrome, Prader-Willi syndrome, isodicentric 15, Bloom syndrome, Marfan syndrome, and Tay-Sachs disease.
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