Dictionary > Chromosome 16

Chromosome 16

Definition
noun
In humans, the autosome that spans about 90 million base pairs, likely to contain about 800 to 900 genes, and is a metacentric chromosome
Supplement
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 16 is a metacentric autosome. It spans almost 90 million base pairs (i.e. about 3 % of the total DNA). It is likely to contain about 800 to 900 genes. Some of the genes found in this chromosome are CARHSP1 (coding for calcium-regulated heat stable protein 1), CKLF (for chemokine-like factor), CTRL (for chymotrypsin-like protease), ERAF (for aAlpha-hemoglobin-stabilizing protein), GLG1 (for Golgi apparatus protein 1), HBAP1 (for hemoglobin, alpha pseudogene 1), and ZNF629 (for zinc finger protein 629).
Some of the diseases and disorders related to the genes on chromosome 16 include trisomy 16, familial Mediterranean fever, thalassemia, Asperger syndrome, synesthesia, and attention deficit hyperactivity disorder.
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