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Chromosome 3

In humans, the autosome that spans almost 200 million base pairs, likely to contain about 1000 to 1100 genes, and is a metacentric chromosome
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 3 is a metacentric autosome. It is one of the largest chromosomes. It spans almost 200 million base pairs (i.e. about 6.5 % of the total DNA). It is likely to contain about 1000 to 1100 genes . On its short arm (p-arm), some of the genes are CCR5 (coding for chemokine receptor 5), GMPPB (for GDP-mannose pyrophosphorylase B), OXTR (for oxytocin receptor), SYNPR (for synaptoporin), and VGLL3 (vestigial-like family member 3). On its long arm (q-arm), some of the genes are ADIPOQ (for adiponectin), MYLK (for telokin), SELT (for selenoprotein T), and SOX2 (for transcription factor). The location of the centromere is metacentric.
Some of the diseases and disorders related to genes on chromosome 3 include autism, cataracts, deafness, diabetes, lymphomas, myotonic dystrophy, night blindness, sucrose intolerance, and Usher syndrome.
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