Dictionary > Chromosome 6

Chromosome 6

In humans, the chromosome that spans more than 170 million base pairs, with likely about 1000 to 1100 genes, and is a submetacentric chromosome
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 6 is a submetacentric autosome. It spans almost 170 million base pairs (i.e. about 5.5 to 6 % of the total DNA). On its short arm (p-arm), some of the genes are DOM3Z (coding for decapping exoribonuclease), G6B (for protein G6b), MLIP (for muscular LMNA interaction protein), TNXB (for tenascin XB), and VPS52 (for GARP complex subunit). On its long arm (q arm), some of the genes are AKIRIN2 (for akirin 2), ARG1 (for arginase 1) , VNN1 (for vanin 1), and VNN2 (for vanin 2).
Some of the diseases and disorders related to the genes on chromosome 6 include hemochromatosis, maple syrup urine disease, epilepsy, and Parkinson disease.
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