Dictionary > Chromosome 7

Chromosome 7

In humans, the chromosome that spans 159 million base pairs, likely to contain about 800 to 1000 genes, and is a submetacentric chromosome
In humans, the chromosomes occur in pairs and a typical somatic cell would contain 23 pairs of chromosomes in the nucleus. Each of these pairs has a characteristic length and banding pattern. There are two types of chromosomes: autosomes and allosomes. There are also two sets: the first set comes from the mother and the second set, from the father. Using idiograms, each chromosome may be identified one from the other based on the relative size and the banding pattern.
Chromosome 7 is a submetacentric autosome. It spans almost 159 million base pairs (i.e. about 5 to 5.5 % of the total DNA). It likely has 800 to 1000 genes. Some of the genes found in chromosome 5 are ACTR3B (coding for actin-related protein 3B), CALU (coding for calumenin), DDX56 (for DEAD-box helicase 56), ICA1 (for islet cell autoantigen 1), NUPL2 (for nucleoporin-like 2), PSPH (for phosphoserine phosphatase), TMEM130 (for transmembrane protein 130), URG4 (for up-regulated gene 4), and ZNF277P (for zinc finger protein 277).
Some of the diseases and disorders related to the genes on chromosome 7 include cystic fibrosis, Marfan syndrome, myotonia congenita, and schizophrenia.
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