Dictionary > Haptenic inhibition

Haptenic inhibition

Haptenic inhibition –>
(Science: immunology molecular biology) Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein).
The hapten constitutes a single antigenic determinant, perhaps the best known example is dinitro phenol (DNP) that can be conjugated to bsa and against which antiDNP antibodies are produced (antibodies to the bsa can be adsorbed out).
Because the hapten is monovalent, immune complex formation will be blocked if the soluble hapten is present as well as the hapten carrier conjugate (assuming there is more than one hapten per carrier then an immune precipitate can be formed).
competitive inhibition by the soluble small molecule is sometimes referred to as haptenic inhibition and this term has carried over into lectin mediated haemagglutination where monosaccharides are added to try to block haemagglutination: the blocking sugar defines the specificity of the lectin.

You will also like...

primitive arthropods

The arthropods were assumed to be the first taxon of species to possess jointed limbs and exoskeleton, exhibit more adva..

Birth of a Human Baby
Birth of a Human Baby

Following nine months inside the mother's womb is the birth of the baby. Know the different stages of the birthing proce..

Geological Periods
Geological Periods

Geological periods is a study guide that cites the different geological periods on Earth's timeline. Each has a brief ov..

running freshwater community
Running Water Freshwater Community Factors

This tutorial noted some of the physical and chemical factors that provide the framework of a running water community in..

Chemical composition of the body
Chemical Composition of the Body

The body is comprised of different elements with hydrogen, oxygen, carbon, and nitrogen as the major four. This tutorial..

bryophyte - sporophyte and gametophyte
Meiosis and Alternation of Generations

Plants are characterized by having alternation of generations in their life cycles. This tutorial is a review of plant m..