Dictionary > Hodgkins disease

Hodgkins disease

Hodgkins disease
(Science: haematology, oncology) a human malgnant disorder of lymph tissue (lymphoma) that appears to originate in a particular lymph node and later spreads to the spleen, liver and bone marrow. It occurs mostly in individuals between the ages of 15 and 35. It is characterised by progressive, painless enlargement of the lymph nodes, spleen and general lymph tissue.
giant cells, the reed Sternberg cells, with mirror image nuclei are diagnostic. Immunological depletion, caused perhaps by the excessive growth of neoplastic histiocytes, occurs.
Four types of the disease are recognised depending on the relative predominance of various neoplastic derivatives of the lymphoid series. Pyrexia is often a feature of the disease.
death often results from generalised immunological inability to respond to infections. If detected early, it has a high remission rate.
Staging: Ann arbor classification; each stage is further classified as:, a no symptoms, B fever, sweats, weight loss.
stage i – involvement of a single lymphnode region or extralymphatic site.
stage II – two or more sites of involvement on the same side of the diaphragm.
stage III – disease involvement on both sides of the diaphragm.
stage ivdisseminated disease of extralymphatic organs, with or without lymphnode involvement.
Indicence: approximately 1,500 new cases per year in the UK.


You will also like...

river
Running Water Freshwater Communities

This tutorial introduces flowing water communities, which bring new and dithering factors into the equation for possible..

Lotic community of algal species
Lotic Communities & Algae

Lotic communities have conditions that are rather harsh for typical plants. Thus, the diversity of plant species in loti..

Chromosome Mutations
Chromosome Mutations

Mutations can also influence the phenotype of an organism. This tutorial looks at the effects of chromosomal mutations, ..

Lights' Effect on Growth
Lights’ Effect on Growth

This tutorial elaborates on the effect of light on plant growth. It describes how different plants require different amo..

Freshwater aquatic plankton
Freshwater Communities & Plankton

Planktons are microscopic organisms that live suspended in aquatic habitats. There are two groups: the phytoplanktons an..

Evolution of Life - Ancient Earth
Evolution of Life – Ancient Earth

Autotrophs flourished, absorbing carbon and light. Soon after, primitive life forms that could assimilate oxygen thrived..