Hyperlipidemia is a condition characterized by the presence of excess amount of lipids in the bloodstream. It may also pertain to the abnormally high level of lipoproteins in the blood although the term hyperlipoproteinemia is sometimes used to refer specifically to this condition. The opposite condition of hyperlipidemia is hypolipidemia wherein the level of lipids (or lipoproteins) in the blood is atypically low. Both of them are forms of dyslipidemia, which is defined as any abnormality in the lipid level in the blood. Hyperlipidemia, though, is more common than hypolipidemia, especially in the developed countries where diet and lifestyle cause elevated lipids. There are two types of hyperlipidemias: primary and secondary. Primary (or familial) hyperlipidemia is associated with genetic factors and it is further classified into the following types:
Secondary (or acquired) hyperlipidemia is essentially non-genetic but occurs as a consequence of other medical conditions, such as diabetes mellitus, kidney failure, and kidney failure, or the use of thiazide diuretics, beta blockers, and other drugs.
Variant: hyperlipidaemia. Synonyms: hyperlip(a)emia, hyperlipoidemia, lip(a)emia, lipid(a)emia, lipoid(a)emia.
- Chait, A. & Brunzell, J. D. (June 1990). “Acquired hyperlipidemia (secondary dyslipoproteinemias)”. Endocrinol. Metab. Clin. North Am. 19 (2): 259–78.
- Fredrickson, D. S. & Lees, R. S. (1965). “A system for phenotyping hyperlipoproteinemia” (PDF). Circulation. 31 (3): 321–27. Retrieved from http://circ.ahajournals.org/cgi/reprint/31/3/321
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