Dictionary > Inbred

Inbred

Definition
noun, plural: inbreds
(1) An individual produced by inbreeding
(2) A population, group, or genetic line that descended over multiple generations, through series of inbreeding
adjective
Produced by inbreeding
Supplement
An inbred pertains to an individual (or a genetic line) that is produced from inbreeding. Inbreeding is a mode of breeding by two individuals or organisms that are closely or genetically related. An inbred may also pertain to a genetic line or a population of a particular species with nearly the same genotype due to long inbreeding. This is particularly referred to as inbred strain in which a strain had undergone a long line of inbreeding, e.g. at about 20, even over a hundred, generations via brother x sister or offspring x parent mating.
In humans, inbreeding is medically discouraged. It is because it could lead to a higher tendency of producing offspring with deleterious traits or congenital birth defects. Mating with a close relative increases the chances of offspring acquiring genes associated with certain genetic disorders. In particular, the homozygosity of a recessive allele for a deleterious trait could lead to its expression. Heterozygosity in the gene pool may be reduced as well due to inbreeding. Greater genetic diversity is essential in increasing the chances of acquiring traits that improve biological fitness and survival. When biological fitness is reduced due to inbreeding, a possible outcome is inbreeding depression.
See also:

Related term(s):

  • Inbred strain
  • Mice inbred mdx
  • Mice inbred hrs
  • Mice inbred cftr


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