Dictionary > Leukocyte inclusion

Leukocyte inclusion

Definition
noun, plural: leukocyte inclusions
Round or oval cytoplasmic inclusion of neutrophils containing remnants of rough endoplasmic reticulum, especially from the proganulocyte stage of cell development.
Supplement
Leukocyte inclusions stain sky blue to grayish blue with Romanowsky stains and about 2 µm in diameter. They represent rapid turnover of cells and toxic granulation. They are commonly found in patients with infections, burns, trauma, pregnancy, or cancer.
Synonym: Dohle body, Dohle inclusion.

See also: Chediak-higashi disease.


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