Dictionary > Mechlorethamine

Mechlorethamine

mechlorethamine
(Science: chemical) A vesicant and necrotizing irritant destructive to mucous membranes. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin’s disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
Pharmacological action: alkylating agents, antineoplastic agent-alkylating, chemical warfare agents, irritants.
Chemical name: Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-


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