(Science: enzyme) An enzyme that catalyses the transfer of aminoacyl-tRNA to formyl–methionine–tRNA or peptidyl-tRNA during peptide chain elongation. It is a part of the 50 s (bacteria) and 60 s (eukaryotes) ribosomal subunits.
integral enzymic activity of the large subunit of a ribosome, catalysing the formation of a peptide bond between the carboxy terminus of the nascent chain and the amino group of an arriving tRNA associated amino acid.
Chemical name: Peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase
Registry number: EC 126.96.36.199