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Rift valley fever virus

Rift valley fever virus is a mosquito-borne arbovirus from the genus Phlebovirus that is responsible for the rift valley fever. Phleboviruses possess a negative-sense RNA genome made up of three segments. These segments are (1) small segment, coding for N protein and nonstructural protein, (2) medium-sized segment, coding for glycoprotein and non-structural components, and (3) large segment, coding for RNA-dependent RNA polymerase. The mode of transmission is by a mosquito vector (often, Culex tritaeniorhynchus and Aedes vexans). The virus may also be contacted by touching or breathing in of an infected animal blood (e.g. during butchering). The virus causes fever, muscle pains, and headaches to its host. When prolonged, the condition could worsen to hemorrhagic fever syndrome, meningoencephalitis, liver problems and loss of sight. Apart from humans, the virus has also been found to infect other animals (e.g. sheep, goats, cattle, and camels) and cause massive hepatitis, abortion, and death. Abbreviation: RVF virus, RVFV.

See also


  1. Modrow, Susanne; Falke, Dietrich; Truyen, Uwe; Schätzl, Hermann. Molecular Virology. Springer. p. 460.
  2. World Health Organization: WHO. (2018, February 19). Rift Valley fever. Retrieved from Who.int website: https://www.who.int/en/news-room/fact-sheets/detail/rift-valley-fever

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