Dictionary > Syndecan


(Science: protein) An integral membrane proteoglycan (250-300 kD) associated largely with epithelial cells.
The core protein of 294 amino acids has an extracellular domain of 235 amino acids and a single transmembrane domain of 25 amino acids. The extracellular domain has up to three heparan sulphate and two chondroitin or dermatan sulphate chains plus an N linked oligosaccharide.
The heparan sulphate chains bind to several proteins of the extracellular matrix, including collagens, fibronectin and tenascin. The cytoplasmic domain is thought to interact with actin filaments. Its name is derived from the greek syndein, to bind together.

You will also like...

Protein (illustration)
Protein Variety

The sequence of amino acids determines the type of protein. Protein is synthesized according to the sequence of nucleoti..

Direct and indirect physiologic effects of growth hormone
Animal Growth Hormones

Hormones are produced in the endocrine glands of animals. The pituitary gland and hypothalamus are the most impor..

Electromagnetic spectrum of a brain
Sleep and Dreams – Neurology

While learning and intelligence are associated with the functions of a conscious mind, sleep and dreams are activities o..

Human Reproduction
Human Reproduction

Humans are capable of only one mode of reproduction, i.e. sexual reproduction. Haploid sex cells (gametes) are produced ..

Genetics – Lesson Outline & Worksheets
Genetics – Lesson Outline & Worksheets

  Topics Modules Quizzes/Worksheets Description Introduction to Genetics Genetics – Definition: Heredity and ..

Plant meristem
Plant Meristems and Growth

In plants, growth occurs in meristems, which are the site of repeated cell division of unspecialized cells. These cells ..