Dictionary > Tandem


term used to describe multiple copies of the same sequence in a polynucleic acid that lie adjacent to one another.
Linkers are short, self-complementary synthetic oligomers which form blunt end duplexes containing a restriction endonuclease recognition sequence. They are used to create cohesive ends on a target dna molecule. Linkers may be obtained with either phosphorylated or unphosphorylated 5′ ends for use in different cloning strategies. Blunt-end ligation of phosphorylated linkers to experimental dna fragments produces concatamers of linkers at both ends of each fragment. Digestion with the appropriate restriction endonuclease creates unique cohesive ends.

You will also like...

Thermographic image of face and neck
Regulation of Organic Metabolism, Growth and Energy Balance

The human body is capable of regulating growth and energy balance through various feedback mechanisms. Get to know the e..

Adaptation Tutorial
Adaptation Tutorial

Adaptation, in biology and ecology, refers to the process or trait through which organisms or the populations in a habit..

Direct and indirect physiologic effects of growth hormone
Animal Growth Hormones

Hormones are produced in the endocrine glands of animals. The pituitary gland and hypothalamus are the most impor..

Physical growth
Physical Development in Humans

This tutorial elaborates on the physical development of humans, particularly from puberty to adulthood. Read this tutori..

"Cronopio dentiacutus", a prehistoric mammal (an illustration)
Mammalian Ancestors

Mammals are a diverse group of organisms, where most of them develop their offspring within the uterus of the mother. Ov..

Schematic diagram of bacterial lactose operon
Gene Action – Operon Hypothesis

Learn how the way genes control and determine every aspect of the body. This lesson uses lac operon as an example. ..