(Science: biochemistry, enzyme) An isomerizing enzyme that during glycolysis, catalyses the reversible interconversion of d-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate and viceversa. A reaction of importance in glycolysis and gluconeogenesis.
A deficiency in humans causes congenital nonspherocytic haemolytic anaemia and severe neurological deficits.
Synonym: phosphotriose isomerase.
chemical name: D-glyceraldehyde-3-phosphate ketol isomerase
registry number: EC 18.104.22.168