Dictionary > Capillary fragility test

Capillary fragility test

Definition
noun
A tourniquet test that is used to determine vitamin C (ascorbic acid) deficiency or thrombocytopenia
Supplement
The capillary fragility test is a test using a blood pressure cuff. The cuff is applied for five minutes to the arm of a person and inflated to a pressure halfway between the systolic and diastolic blood pressure. Petechiae within the circumscribed skin area are then counted 1 Ten petechiae per square inch is considered normal, ten to twenty, marginal. Petechiae that are more than twenty per square inch are beyond the acceptable normal range and therefore the test indicates positive to vitamin C deficiency or thrombocytopenia.
This test used to be incorporated by the WHO as part of the algorithm for the diagnosis of dengue fever.2 However, because of the low sensitivity of the test, this is no longer recommended in the recent WHO guidance in the classification test for dengue haemorraghic fever.
Synonym(s):

  • tourniquet test
  • capillary resistance test
  • vitamin c test
  • rumpel-leede test (sign)

See also:

  • Bandage sign

Reference(s):

1 tourniquet test. (n.d.) Mosby’s Medical Dictionary, 8th edition. (2009). Retrieved from http://medical-dictionary.thefreedictionary.com/tourniquet+test

2 WHO (2009). Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control. Retrieved from http://whqlibdoc.who.int/publications/2009/9789241547871-eng.pdf


You will also like...

Kidneys
Kidneys and Regulation of Water and Inorganic Ions

The kidneys are responsible for the regulation of water and inorganic ions. Read this tutorial to learn about the differ..

mRNA
Protein Synthesis

Part of the genetic information is devoted to the synthesis of proteins. mRNA, a type of RNA, is produced as a transcri..

Genetics and Evolution
Genetics and Evolution

Humans are diploid creatures. This means that for every chromosome in the body, there is another one to match it. Howeve..

Neurology of Illusions
Neurology of Illusions

Illusions are the perceptions and sensory data obtained from situations in which human error prevents us from seeing the..

Ecological Research Measuring & Analysis
Ecological Research: Measuring & Analysis

This lesson is about the methods used for ecological research, such as quadrat and transect sampling, canopy fogging, an..

Thermographic image of face and neck
Regulation of Organic Metabolism, Growth and Energy Balance

The human body is capable of regulating growth and energy balance through various feedback mechanisms. Get to know the e..