Dictionary > Christmas factor

Christmas factor

Definition
noun
A blood clotting factor in the intrinsic pathway of the blood coagulation cascade and works with clotting factor VIII (antihaemophilic factor) and calcium to activate clotting factor X (Stuart factor)
Supplement
Coagulation, the process of clot formation, involves platelet and blood clotting factors. In humans, the coagulation mechanism is comprised of two processes, i.e. the primary hemostasis and the secondary hemostasis. The latter entails two pathways: (1) intrinsic pathway (contact activation pathway) and (2) extrinsic pathway (tissue factor pathway). Both pathways lead to the formation of fibrin.
The clotting factor IX is also known as Christmas factor. The name is derived from the boy, Stephen Christmas. He was lacking this factor and the deficiency led him to acquire hemophilia. The Christmas factor is produced from the liver. Its production is activated by clotting factor XI (plasma prothromboplastin antecedent) and calcium.
The Christmas factor, when activated to clotting factor IXa, works with clotting factor VIII (antihaemophilic factor) and calcium to activate clotting factor X (Stuart factor).
Deficiency of factor ix results in Christmas disease (haemophilia b).
Synonym(s):

  • coagulation factor IX
  • clotting factor IX
  • factor IX
  • plasma thromboplastic component
  • blood-coagulation factor IX
  • plasma thromboplastin component
  • antihemophilic factor B

See also:

  • clotting factor
  • coagulation
  • clotting factor VIII
  • clotting factor X
  • Christmas disease
  • Related term(s):

    • Christmas factor assay


    You will also like...

    Lotic community of algal species
    Lotic Communities & Algae

    Lotic communities have conditions that are rather harsh for typical plants. Thus, the diversity of plant species in loti..

    Bryophytes
    Bryophytes

    Bryophytes (nonvascular plants) are a plant group characterized by lacking vascular tissues. They include the mosses, th..

    Oligodendrocyte and Schwann cell
    The Central Nervous System

    Myelin sheath is essential for a faster conductivity of signals. Know more about this feature of some neurons in the Cen..

    Selective Breeding
    Selective Breeding

    Gregor Mendel's studies into Monohybrid and Dihybrid crossing and Charles Darwin's study of evolution and natural select..

    Crossing Over and Genetic Diversity
    Inheritance and Probability

    Gregor Mendel, an Austrian monk, is most famous in this field for his study of the phenotype of pea plants, including ..

    An artistic depiction of Dunkleosteus fish
    Fish

    The sea was teeming with life. Eventually, through reproduction and continued variation, fish came about. There are over..

    Related Articles...

    No related articles found

    See all Related Topics