Dictionary > Christmas factor

Christmas factor

Definition
noun
A blood clotting factor in the intrinsic pathway of the blood coagulation cascade and works with clotting factor VIII (antihaemophilic factor) and calcium to activate clotting factor X (Stuart factor)
Supplement
Coagulation, the process of clot formation, involves platelet and blood clotting factors. In humans, the coagulation mechanism is comprised of two processes, i.e. the primary hemostasis and the secondary hemostasis. The latter entails two pathways: (1) intrinsic pathway (contact activation pathway) and (2) extrinsic pathway (tissue factor pathway). Both pathways lead to the formation of fibrin.
The clotting factor IX is also known as Christmas factor. The name is derived from the boy, Stephen Christmas. He was lacking this factor and the deficiency led him to acquire hemophilia. The Christmas factor is produced from the liver. Its production is activated by clotting factor XI (plasma prothromboplastin antecedent) and calcium.
The Christmas factor, when activated to clotting factor IXa, works with clotting factor VIII (antihaemophilic factor) and calcium to activate clotting factor X (Stuart factor).
Deficiency of factor ix results in Christmas disease (haemophilia b).
Synonym(s):

  • coagulation factor IX
  • clotting factor IX
  • factor IX
  • plasma thromboplastic component
  • blood-coagulation factor IX
  • plasma thromboplastin component
  • antihemophilic factor B

See also:

  • clotting factor
  • coagulation
  • clotting factor VIII
  • clotting factor X
  • Christmas disease
  • Related term(s):

    • Christmas factor assay


    You will also like...

    Adaptive Radiation
    Adaptive Radiation

    The diversification of several new species from a recent ancestral source, each adapted to utilize or occupy a vacant ad..

    Biological Cell Defense
    Biological Cell Defense

    Organisms employ different strategies to boost its defenses against antigens. Humans have an immune system to combat pat..

    Regulation of Biological Systems
    Regulation of Biological Systems

    Regulation of Biological Systems tutorials are focused on the modulation of biological systems from cell to population l..

    Birth of a Human Baby
    Birth of a Human Baby

    Following nine months inside the mother's womb is the birth of the baby. Know the different stages of the birthing proce..

    Sugar Homeostasis
    Sugar Homeostasis

    The blood sugar level is regulated by two hormones. The mechanism behind this type of negative feedback control is descr..

    Buttress roots
    Roots

    This study guide tackles plant roots in greater detail. It delves into the development of plant roots, the root structur..