Dictionary > Elephantiasis

Elephantiasis

Definition
noun, plural: elephantiases
A disease of the skin characterized by being thick, rough, hard, and fissured, like an elephant hide
Supplement
Elephantiasis is a thickening and hardening of a body part, i.e. akin to an elephant hide. It may be a symptom of a variety of diseases, such as elephantiasis nostras, elephantiasis tropica (lymphatic filariasis), nonfilarial elephantiasis (podoconiosis), proteus syndrome, etc.
In elephantiasis nostras, the disease affects the legs or scrotum. It resembles the filarial elephantiasis (elephantiasis tropica). However, it results as a complication of chronic lymphedema and not because of filariasis. Nevertheless, both of them results in excess fluid accumulation due to an impaired lymphatic drainage. Another nonfilarial-type of elephantiasis, the podoconiosis, is one in which the swelling is caused by an immune disease affecting the lymph vessels. Proeteus syndrome is a rare congenital disorder resulting in skin overgrowth and atypical bone development.
Elephantiasis caused by filarial roundworm is a complication of chronic filariasis, especially when the filariasis is left untreated for too long. Three types of filarial worms are associated with this disease. They are Wuchereria bancrofti, Brugia malayi, and Brugia timori. They typically occupy the lymphatic system of the definitive host. The filarial worms spread from one human host to another through a mosquito vector that feed on blood of humans, especially at nighttime.
Word origin: Greek elephantos (“elephant”) + –iasis (disease, morbid condition)
See also:

  • filariasis
  • lymphatic filariasis
  • nematode


You will also like...

Digestion and Absorption of Food
Digestion and Absorption of Food

The gastrointestinal system breaks down particles of ingested food into molecular forms by enzymes through digestion and..

Structural depiction of catalase, an enzyme
Protein Activity and Cellular Metabolism

Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..

The Human Physiology
The Human Physiology

Physiology is the study of how living organisms function. Thus, human physiology deals specifically with the physiologic..

Lights' Effect on Growth
Lights’ Effect on Growth

This tutorial elaborates on the effect of light on plant growth. It describes how different plants require different amo..

Direct and indirect physiologic effects of growth hormone
Animal Growth Hormones

Hormones are produced in the endocrine glands of animals. The pituitary gland and hypothalamus are the most impor..

Protein (illustration)
Protein Variety

The sequence of amino acids determines the type of protein. Protein is synthesized according to the sequence of nucleoti..

Related Articles...

No related articles found

See all Related Topics