Dictionary > Gap 0 phase

Gap 0 phase

The phase in the cell cycle wherein the cell is in inactive or non-cycling state following cell division
In eukaryotes, the cell cycle is a cyclical series of biological events that certain asexual cells go through. In essence, the cell cycle is highlighted by a sequence of events such as the duplication of DNA via DNA replication, in preparation to cell division wherein the parent cell divides and gives rise to two genetically identical daughter cells. The cell cycle is comprised of these fundamental events: (1) resting phase (Gap 0), (2) interphase (Gap 1, S phase, Gap 2), and (3) cell division (i.e. mitotic phase and cytokinesis).
Gap 0 phase is also referred to as the resting phase. It is because it is in this phase when the cell following cell division enters a resting period. The cell is inactive in a way that it exits the cell cycle and is not preparing itself to undergo cell division. It is a way of the cell to preserve important physiologic function for a longer period of time. This phase may be irreversible or reversible depending on the cells involved. For instance, tissue stem are cells (e.g. muscle stem cells, intestinal stem cells, neural stem cells, etc.) remain in Gap 0 phase and be in a quiescent state for an indefinite period until external stimuli activate them into re-entering the remaining phases of the cell cycle all through cell division. Irreversible Gap 0 phase (i.e. terminal Gap 0) is observed among senescent cells, as well as fully differentiated cells such as myocytes, osteocytes, etc.
Abbreviation / Acronym: G0 (phase)

  • resting phase

See also:

  • cell cycle
  • mitosis
  • interphase

    You will also like...

    green leaf - close up view

    Leaves are the major photosynthetic organ of a plant. Apart from that, they are also crucial to water movement. In this ..

    Community Patterns

    Learn about community patterns and the ecological factors influencing these patterns. Revisit some of the ecosystems you..

    Still freshwater and plants
    Still Freshwater & Plants

    Plants in lentic habitats have features not found in terrestrial plants. They acquired these features as they adapt to t..

    Body temperature regulation by the hypothalamus
    Temperature Regulation in Animals

    This tutorial elucidates body temperature regulation. Know the details here to learn how the body sets the body temperat..

    Nephrolepis exaltata
    Vascular Plants: Ferns and Relatives

    Ferns and their relatives are vascular plants, meaning they have xylem and phloem tissues. Because of the presence of va..

    Homeostatic Mechanisms and Cellular Communication
    Homeostatic Mechanisms and Cellular Communication

    Homeostasis is the relatively stable conditions of the internal environment that result from compensatory regulatory res..