Dictionary > Gout

Gout

Gout
(Science: rheumatology) recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected.
The arthritis occurs secondary to an inherited Abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage.
Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion.


You will also like...

Electromagnetic spectrum of a brain
Sleep and Dreams – Neurology

While learning and intelligence are associated with the functions of a conscious mind, sleep and dreams are activities o..

Human gastrointestinal tract
Human Biology – Food and Digestion

This tutorial recognizes the importance of food as a source of energy that will fuel many biological processes. A good d..

Crossing Over and Genetic Diversity
Inheritance and Probability

Gregor Mendel, an Austrian monk, is most famous in this field for his study of the phenotype of pea plants, including ..

river
Running Water Freshwater Communities

This tutorial introduces flowing water communities, which bring new and dithering factors into the equation for possible..

Freshwater aquatic plankton
Freshwater Communities & Plankton

Planktons are microscopic organisms that live suspended in aquatic habitats. There are two groups: the phytoplanktons an..

Plant Water Regulation
Plant Water Regulation

Plants need to regulate water in order to stay upright and structurally stable. Find out the different evolutionary adap..

Related Articles...

No related articles found

See all Related Topics