Dictionary > Hatch-Slack pathway

Hatch-Slack pathway

A metabolic pathway first delineated in depth by M. D. Hatch and C. R. Slack (in 1966).
In this pathway, the CO2 is first added to phosphoenolpyruvate by the enzyme, PEP carboxylase, producing the four-carbon compound in mesophyll cells that is later transported to bundle sheath cells to liberate the CO2 for use in the Calvin cycle.
Instead of the direct carbon fixation in the Calvin cycle like in C3 carbon fixation, the C4 pathway involves steps that first converts pyruvate to phosphoenolpyruvate (PEP) to bind with the CO2 forming a four-carbon compound (hence the name C4). As a result, the photorespiration pathway is bypassed, and the wasteful loss of CO2 common in C3 carbon fixation pathway is minimized.
Plants that first go through the C4 pathway are better adapted than plants that solely go through the C3 pathway under conditions of drought, high temperatures and low nitrogen or CO2 concentrations.
Word origin: from M.D. Hatch and C.R. Slack who first described it.
Synonym: Hatch slack kortshak pathway, C4 carbon fixation pathway.

Compare: C3 carbon fixation pathway, Crassulacean acid metabolism.

See also: C4 plant.

You will also like...

Birth Control and Contraception
Birth Control and Contraception

Different pregnancy and birth control and contraception strategies are described. Read this tutorial to learn each of th..


The circulatory system is key to the transport of vital biomolecules and nutrients throughout the body. Learn about the ..

The Dinosaurs

Dinosaurs represented a major turn in the evolutionary development of organisms on Earth. The first dinosaurs were presu..

Golgi apparatus (3-D illustration)
Role of Golgi Apparatus & Endoplasmic Reticulum in Protein Synthesis

The endoplasmic reticulum and Golgi apparatus are the organelles involved in the translation step of protein synthesis a..

Genetics – Lesson Outline & Worksheets
Genetics – Lesson Outline & Worksheets

  Topics Modules Quizzes/Worksheets Description Introduction to Genetics Genetics – Definition: Heredity and ..

Sigmund Freud and Carl Gustav Jung
Sigmund Freud and Carl Gustav Jung

In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..