Dictionary > Hsk pathway

Hsk pathway

An abbreviation for hatch slack kortshak pathway: a metabolic pathway first determined by Burr and Kortshak in their experiments that later led to its in-depth description by M. D. Hatch and C. R. Slack (in 1966).
In this pathway, the CO2 is first added to phosphoenolpyruvate by the enzyme, PEP carboxylase, producing the four-carbon compound in mesophyll cells that is later transported to bundle sheath cells to liberate the CO2 for use in the Calvin cycle.
Instead of the direct carbon fixation in the Calvin cycle like in C3 carbon fixation, the C4 pathway involves steps that first converts pyruvate to phosphoenolpyruvate (PEP) to bind with the CO2 forming a four-carbon compound (hence the name C4). As a result, the photorespiration pathway is bypassed, and the wasteful loss of CO2 common in C3 carbon fixation pathway is minimized.
Plants that first go through the C4 pathway are better adapted than plants that solely go through the C3 pathway under conditions of drought, high temperatures and low nitrogen or CO2 concentrations.
Synonym: Hatch slack kortshak pathway, C4 carbon fixation pathway.

Compare: C3 carbon fixation pathway, Crassulacean acid metabolism.

See also: C4 plant.

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