Dictionary > Intrinsic sympathomimetic activity

Intrinsic sympathomimetic activity

Definition
noun
The property of a drug that produces partial agonist effect at the receptor similar to the cholinergic stimulation of the sympathetic nervous system.
Supplement
Intrinsic sympathomimetic activity or ISA is often used to describe the property of certain beta-blockers.
Beta-blockers with ISA are beta-blockers that exert a partial agonism at the adrenergic receptor while simultaneously blocking the endogenous catecholamines from binding to the receptor. Hence, they are less potent than catecholamines and other beta-agonists.
Acronym: ISA.

See also: agonism, beta-blocker.


You will also like...

Flowers and tiny fruits of the pomegranate plant
Fruits, Flowers, and Seeds

This tutorial deals with the structure and function of flowers, fruits, and seeds. Also included here are the types of f..

Gibberellins and Gibberellic Acid
Gibberellins and Gibberellic Acid

This tutorial describes the role of gibberellin family in plants. Find out the effects of gibberellin on plant growth an..

Homeostatic Mechanisms and Cellular Communication
Homeostatic Mechanisms and Cellular Communication

Homeostasis is the relatively stable conditions of the internal environment that result from compensatory regulatory res..

Non-Mendelian Inheritance
Non-Mendelian Inheritance

In this tutorial, find out more about certain types of inheritance that does not follow the Mendelian inheritance patter..

IQ, Creativity and Learning
IQ, Creativity and Learning

Human intelligence provided the means to utilize abstract ideas and implement reasoning. This tutorial takes a further l..

Still Water Community Plants
Still Water Community Plants

This tutorial looks at the adaptations of freshwater plants for them to thrive in still water habitats. Familiarize your..