Dictionary > Megakaryoblast

Megakaryoblast

Definition
noun, plural: megakaryoblasts
A precursor cell that develops into a promegakaryocyte during thrombopoiesis
Supplement
Hematopoiesis is the process of forming new blood cellular elements in vertebrates. In this regard, thrombopoiesis is a hematopoiesis leading to the formation of thrombocytes. It begins with a multipotent stem cell, a hemocytoblast, which gives rise to a common myeloid progenitor cell. The progenitor cell, in turn gives rise to colony forming unit (particularly, CFU-Me, which is also referred to as CFU-Meg or CFU-Mega) fated to become megakaryocytes. The CFU-Me gives rise to megakaryoblasts. A megakaryoblast is a committed progenitor cell that gives rise to promegakaryocytes. In the thrombocytic series, the megakaryoblast is at the beginning of the series, prior to promegakaryocytic stage.
The megakaryoblast is a cell that ranges from 8μm to 30μm in size. It has a large nucleus with an oval or a round shape. Its nucleus is about three to five times the size of its cytoplasm. There are several nucleoli present in the nucleus.
Word origin: Greek mégas (“large”) + Greek karuo– (“nut”) + Greek blastos (“germ“, “sprout”)
See also:

Related form(s):

  • megakaryoblastic (adjective, of, relating to, or pertaining to a megakaryoblast)


  • You will also like...

    Energy pyramid
    Freshwater Community Energy Relationships – Producers & Consumers

    This tutorial looks at the relationship between organisms. It also explores how energy is passed on in the food chain an..

    Endemic Flora of New Zealand
    New Zealand’s Unique Flora

    If New Zealand has lots of unique animals, it's also got a whole lot of unique plants. Find out more about some of them,..

    Cambial cells
    Plant Tissues

    Plant organs are comprised of tissues working together for a common function. The different types of plant tissues are m..

    Regulation of Biological Systems
    Regulation of Biological Systems

    Regulation of Biological Systems tutorials are focused on the modulation of biological systems from cell to population l..

    Bryophytes
    Bryophytes

    Bryophytes (nonvascular plants) are a plant group characterized by lacking vascular tissues. They include the mosses, th..

    "Cronopio dentiacutus", a prehistoric mammal (an illustration)
    Mammalian Ancestors

    Mammals are a diverse group of organisms, where most of them develop their offspring within the uterus of the mother. Ov..

    Related Articles...

    No related articles found

    See all Related Topics