Dictionary > Memory B cell

Memory B cell

Definition
noun, plural: memory B cells
A small, long-lived B lymphocyte that was previously exposed to a particular antigen, and then proliferates and produces large amounts of antibodies during re-exposure to the same antigen
Supplement
B lymphocytes, also called B cells, are types of lymphocytes involved in the production of immunoglobulins, thus, in the humoral immune response of the adaptive immune system. There are many types of B lymphocytes (or B cells): plasma B cells, memory B cells, B-1 cells, B-2 cells, marginal-zone B cells, and regulatory B cells.
B cells come from the bone marrow. They are, then, released into the blood and the lymphatic system. B cell that encountered an antigen turns into an antigen-presenting cell. In the germinal centers of secondary lymphoid organs such as spleen and lymph nodes, the Helper T cell recognizes the signal (antigenic peptide) and activates the antigen-presenting B cell to proliferate. The clones that the parent B cell produces may differentiate into plasma cells or memory B cells.
A memory B cell is a dormant B cell. It is involved in the secondary immune response. It circulates throughout the body and produces a more robust antibody-mediated immune response when exposed again to the same antigen (re-infection). Since the memory B cell is a clone, it would have the same B cell receptors (BCRs) as its parent B cell and therefore would be able to detect the same antigen.
A memory B cell is different from a plasma B cell in a way that it persists longer than a plasma cell.
See also:


You will also like...

Geological Periods
Geological Periods

Geological periods is a study guide that cites the different geological periods on Earth's timeline. Each has a brief ov..

Human Nervous System
The Human Nervous System

The nervous system is essentially a biological information highway. This tutorial gives an overview of the nervous syste..

New Zealand Flora & Fauna
Ecology & Biodiversity: New Zealand Flora & Fauna

New Zealand is known for its unique biodiversity, caused by its remarkable geography and geologic history. Breaking away..

Cell structure
Cell Structure

A typical eukaryotic cell is comprised of cytoplasm with different organelles, such as nucleus, endoplasmic reticulum, G..

Neural Control Mechanisms
Neural Control Mechanisms

Neurons generate electric signals that they pass along to the other neurons or target tissues. In this tutorial, you wil..

Chromosomes X and Y and Sex Determination
Chromosomes X and Y and Sex Determination

This tutorial looks at sex determination via the sex chromosomes, X and Y. Read it to get more info on X and Y chromosom..