Dictionary > Memory B cell

Memory B cell

Definition
noun, plural: memory B cells
A small, long-lived B lymphocyte that was previously exposed to a particular antigen, and then proliferates and produces large amounts of antibodies during re-exposure to the same antigen
Supplement
B lymphocytes, also called B cells, are types of lymphocytes involved in the production of immunoglobulins, thus, in the humoral immune response of the adaptive immune system. There are many types of B lymphocytes (or B cells): plasma B cells, memory B cells, B-1 cells, B-2 cells, marginal-zone B cells, and regulatory B cells.
B cells come from the bone marrow. They are, then, released into the blood and the lymphatic system. B cell that encountered an antigen turns into an antigen-presenting cell. In the germinal centers of secondary lymphoid organs such as spleen and lymph nodes, the Helper T cell recognizes the signal (antigenic peptide) and activates the antigen-presenting B cell to proliferate. The clones that the parent B cell produces may differentiate into plasma cells or memory B cells.
A memory B cell is a dormant B cell. It is involved in the secondary immune response. It circulates throughout the body and produces a more robust antibody-mediated immune response when exposed again to the same antigen (re-infection). Since the memory B cell is a clone, it would have the same B cell receptors (BCRs) as its parent B cell and therefore would be able to detect the same antigen.
A memory B cell is different from a plasma B cell in a way that it persists longer than a plasma cell.
See also:


You will also like...

Protein (illustration)
Protein Variety

The sequence of amino acids determines the type of protein. Protein is synthesized according to the sequence of nucleoti..

Structural depiction of catalase, an enzyme
Protein Activity and Cellular Metabolism

Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..

Community Patterns

Learn about community patterns and the ecological factors influencing these patterns. Revisit some of the ecosystems you..

vitamins
A Balanced Vitamin Diet – Vitamins A – K

A balanced diet is essential to a healthy organism. Insufficiency or too much of a particular element or compound, such ..

Neurology of Illusions
Neurology of Illusions

Illusions are the perceptions and sensory data obtained from situations in which human error prevents us from seeing the..

Carbohydrates, fats and proteins - dietary sources
A Balanced Diet – Carbohydrates and Fat

Apart from vitamins, the human body also requires high energy sources such as carbohydrates and fats. If you want an ove..