Dictionary > Positional cloning

Positional cloning

Positional cloning is a gene identification method to determine the position of a gene in the genome and not necessarily its function. The chromosomal location is initially determined from linkage analysis and referred to as the candidate region. To further narrow down the candidate region, positional cloning is carried out. Because this is the reverse of how things have been traditionally done, it has also been called reverse genetics.

See also


© Biology Online. Content provided and moderated by Biology Online Editors



You will also like...

Peppered moth ("Biston betularia") melanic and light form
Examples of Natural Selection

Darwin's Finches are an example of natural selection in action. They are an excellent example of the way species' gene p..

Adaptive Radiation
Adaptive Radiation

The diversification of several new species from a recent ancestral source, each adapted to utilize or occupy a vacant ad..

Pikas are an indicator species for climate change
Indicator Species and Endangered Species

Certain species are capable of expressing characteristics indicative of the state of the ecosystem they occupy. They are..

human brain structure
The Conscious & Unconscious Nervous System

This tutorial elaborates on how the nervous system works, particularly at the tissue level of the brain. There are three..

Gene Pool and Speciation
The Gene Pool and Population Genetics

According to Charles Darwin's theory of natural selection, preferable genes are favored by nature in the gene pool, and ..

Transpiration
Water in Plants

The movement of molecules (specifically, water and solutes) is vital to the understanding of plant processes. This tuto..

Related Articles...

No related articles found

See all Related Topics