Dictionary > Proerythroblast

Proerythroblast

Definition
noun, plural: proerythroblasts
A progenitor cell that arises from the CFU-e, and then develops to become an erythroblast (or normoblast)
Supplement
In vertebrates, including humans, blood is the fluid that circulates in the body to deliver nutrients and oxygen. It is comprised of the plasma and the cellular elements. The cellular elements are the blood cells and the platelets, which are all derived from multipotent stem cells. A hemocytoblast is a multipotent hematopoietic stem cell that gives rise to both lymphoid and myeloid stem cells. The myeloid stem cells are progenitor cells that give rise to erythrocytes, granulocytes, monocytes, and megakaryocytes. The process by which a progenitor cell differentiates into an erythrocyte is referred to as erythropoiesis. A proerythroblast is a cell in the earliest stages of erythropoiesis. It is the precursor cell for erythroblast (or normoblast).
Proerythroblast is sometimes used synonymously with pronormoblast. However, a stricter definition of a proerythroblast would be one that includes both pronormoblast and promegalobast. A pronormoblast is a form of proerythroblast that would undergo normal development whereas a promegaloblast is a form of proerythroblast that undergoes an abnormal development. Thus, a proerythroblast would be an inclusive term for both pronormoblast and promegaloblast.
Proerythroblast is derived from a CFU-e. It becomes a cell that is committed to become an erythrocyte via erythropoiesis. To become one, it develops into an erythroblast (or normoblast), which then develops into a reticulocyte, and then finally into an erythrocyte.
Synonym(s):

  • pronormoblast
  • rubriblast

See also:

  • blood cell
  • erythropoiesis
  • normoblast


  • You will also like...

    kinesin motor proteins transporting molecules across microtubules
    Movement of Molecules Across Cell Membranes

    Molecules move within the cell or from one cell to another through different strategies. Transport may be in the form of..

    Flowers and tiny fruits of the pomegranate plant
    Fruits, Flowers, and Seeds

    This tutorial deals with the structure and function of flowers, fruits, and seeds. Also included here are the types of f..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

    Wart-like leaf galls on grape leaves
    Plant Cell Defense

    Plants protect themselves by releasing hydrogen peroxide to fight against fungal invasion. Another way is by secreting c..

    Darwin's Finches - Natural Selection
    Darwin and Natural Selection

    This tutorial investigates the genetic diversity in more detail. It also delineates how certain alleles are favored over..

    Freshwater aquatic plankton
    Freshwater Communities & Plankton

    Planktons are microscopic organisms that live suspended in aquatic habitats. There are two groups: the phytoplanktons an..

    Related Articles...

    No related articles found

    See all Related Topics