Dictionary > Rebound phenomenon

Rebound phenomenon

Definition
noun
(1) A temporary deviation from a normal state in the opposite direction following an abrupt removal or discontinuation of a variable, such as a treatment suddenly discontinued after a long-term use, a passive resistance released suddenly, an undershoot, etc., in an effort to restore balance or homeostasis
(2) A condition wherein the maximum therapeutic effect is reached, and the opposite effect ensues
Supplement
For example, a rebound phenomenon occurs when the sudden discontinuation of medication results in the relapse of symptoms that are worse than those before the treatment. Thus, treatments capable of causing rebound effects have to be withdrawn gradually. Another example is the posthypoglycemic hyperglycemia characterized by a rebound hyperglycemia after a period of hypoglycemia. When the blood glucose level is low the body tends to compensate by producing regulatory hormones that incite the liver to produce glucose from stored glycogen. Thus, the outcome is an increase of blood glucose or hyperglycemia. Another is the Stewart-Holmes sign seen in individuals with cerebellar deficit or a lesion in the cerebellum.
Rebound phenomenon is also described when rebound effects ensues after the individual developed tolerance to the drug. An example is the prolonged use of pain killers that lead to the development of tolerance to these drugs. Eventually, the pain killers become less effective. This leads to headaches that are more frequent or worse than before.
Word origin: French rebondir + Greek phainomenon anything seen
Also called:

  • rebound effect

See also:

  • Stewart-Holmes test
  • Somogyi phenomenon


  • You will also like...

    Human gastrointestinal tract
    Human Biology – Food and Digestion

    This tutorial recognizes the importance of food as a source of energy that will fuel many biological processes. A good d..

    human respiratory system
    Respiration

    The human respiratory system is an efficient system of inspiring and expiring respiratory gases. This tutorial provides ..

    Early Earth
    The Origins of Life

    This tutorial digs into the past to investigate the origins of life. The section is split into geological periods in the..

    Lake Wakatipu, New Zealand
    New Zealand’s Unique Geographical History

    Explore why New Zealand has such unique flora and fauna, and learn why long periods of geographical isolation. This less..

    Gibberellins and Gibberellic Acid
    Gibberellins and Gibberellic Acid

    This tutorial describes the role of gibberellin family in plants. Find out the effects of gibberellin on plant growth an..

    dinosaurs
    The Dinosaurs

    Dinosaurs represented a major turn in the evolutionary development of organisms on Earth. The first dinosaurs were presu..

    Related Articles...

    No related articles found

    See all Related Topics