Dictionary > Wagners syndrome

Wagners syndrome

Definition
noun
(1) A degenerative condition of the vitreous and retinal parts of the eye, and may eventually lead to progressive vision loss.
(2) A disease of the connective tissue in the eye that can be inherited in an autosomal dominant pattern.
Supplement
Wagner syndrome is a very rare hereditary vitreo-retinal disease. It is one of the connective tissue disorders affecting the collagen.
The main feature is an ‘empty’ vitreous that lacks the normal structure. Missing or weak vasculature in the peripheral retina makes the retina prone to tear or getting detached. Diminished visual acuity at night is also a problem as is the early onset of cataract (from the age of 30) and choroidal atrophy. A lot of people are moderate (> -2) to highly (> -6) myopic. Wagner syndrome is ocular only.
The genetic cause for Wagner syndrome has been found in 2005. The gene responsible for this disorder is the Versican gene (5q13.4). About 20 families with Wagner syndrome have been found in Switzerland, the Netherlands, France, the UK, the USA and Japan.
For more information see: www.wagnersyndrome.eu
Word origin: first described by Hans Wagner in 1938 on Canton Zurich family with vitreous and retinal lesions.
Synonym: Wagner’s hyaloid retinal degeneration, Wagner’s vitreoretinal herdodegeneration, Wagners disease.


You will also like...

Stem
Stems

Stems primarily provide plants structural support. This tutorial includes lectures on the external form of a woody twig ..

Population Regulation in an Ecosystem
Population Regulation in an Ecosystem

With regard to the population size of a species and what factors may affect them, two factors have been defined. They ar..

Structural depiction of catalase, an enzyme
Protein Activity and Cellular Metabolism

Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..

Gibberellins and Gibberellic Acid
Gibberellins and Gibberellic Acid

This tutorial describes the role of gibberellin family in plants. Find out the effects of gibberellin on plant growth an..

genes controlling growth and development
Control of Growth & Development

Control of Growth & Development tutorials look at how the genetic makeup determines the biological processes on a da..

Cambial cells
Plant Tissues

Plant organs are comprised of tissues working together for a common function. The different types of plant tissues are m..

Related Articles...

No related articles found

See all Related Topics