Dictionary > Active agglutination

Active agglutination

Definition
noun
An agglutination reaction in which the antigen is found naturally on particle
Supplement
Agglutination pertains to the clumping together of antibodies with antigen-presenting cells, such as red blood cells and microorganisms. Agglutination is used for medical diagnostic tests, particularly for identifying bacterial antigens and therefore the identity of the bacteria as well. It is also the underlying principle of hemagglutination (the clumping of red blood cells together). Agglutination is a two-step process: it starts with sensitization and then to lattice formation.
There are two forms of agglutination. They are the active agglutination and the passive agglutination. With active agglutination, the antigen occurs naturally on particle. With passive agglutination, the antigen must first be bound to an inert particle to detect an antibody.
Examples of active agglutination include the blood grouping, the bacterial serotyping, such as Salmonella, test serum against bacteria that are difficult to grow in culture, such as ”Tularemia, Rickettsial diseases, typhoid fever, and hemagglutination kits for measles antibody detection1
Compare:

Synonym(s):

  • direct agglutination
  • See also:

    • biological technique
    • agglutination reaction
    • antigen
    • antiserum
    • sorption
    • spontaneous aggtination
    • immune agglutination
    • group agglutination

    Related term(s):

  • agglutination
  • Reference(s):

    1 Terry Kotria. 2.Basic Immunology Procedure. Austin Community College. October 2010. www.austincc.edu/kotrla/SerLec2.pdf link


    You will also like...

    New Zealand Fauna
    New Zealand’s Unique Fauna

    Meet some of New Zealand's unique fauna, including endemic insects, frogs, reptiles, birds, and mammals, and investigate..

    Mātauranga Māori and Science Collaboration
    Mātauranga Māori and Science

    Mātauranga Māori is the living knowledge system of the indigenous people of New Zealand, including the relationships t..

    Buttress roots
    Roots

    This study guide tackles plant roots in greater detail. It delves into the development of plant roots, the root structur..

    Biological Viruses
    Biological Viruses

    Viruses possess both living and non-living characteristics. This unique feature distinguishes them from other organisms...

    Nephrolepis exaltata
    Vascular Plants: Ferns and Relatives

    Ferns and their relatives are vascular plants, meaning they have xylem and phloem tissues. Because of the presence of va..

    Peppered moth ("Biston betularia") melanic and light form
    Examples of Natural Selection

    Darwin's Finches are an example of natural selection in action. They are an excellent example of the way species' gene p..

    Related Articles...

    No related articles found

    See all Related Topics