Dictionary > Autoimmunity

Autoimmunity

Definition
noun, plural: autoimmunities
A type of immunity wherein the immune response is directed against own body, attacking own tissues, cells, or cell components
autoimmune
(immunology) Of, relating to, or pertaining to autoimmunity
Supplement
Autoimmunity is characterized by the body turning against own cells, cell components, or tissues through a system of immune responses. In humans, for instance, the immune response entails different mechanisms to attack pathogens or antigens thereby protecting the body from diseases. The immune responses include antibody production, induction of cell-mediated immunity, complement activation, and development of immunological tolerance. Immune cells such as lymphocytes attack antigens such as pathogenic microbes. Antibodies are produced by B lymphocytes in order to identify and neutralize antigens. In autoimmunity, the immune response is directed against certain cells and tissues of the body. Some autoimmune responses may lead to autoimmune diseases such as Celiac disease, Sarcoidosis, systemic lupus erythematosus, Churg-Strauss Syndrome, Sjögren’s syndrome, diabetes mellitus type 1, idiopathic thrombocytopenic purpura, Addison’s Disease, Hashimoto’s thyroiditis, Graves’ disease, and rheumatoid arthritis. Nevertheless, other autoimmune responses are hypothesized to be a normal part of the immune system, which is referred to as natural autoimmunity.1
Word origin: auto ‎(self) + immunity
See also:

Reference(s):

1 Poletaev, A. B., Churilov, L. P., Stroev, Y. I, and Agapov, M. M. (2012). “Immunophysiology versus immunopathology: Natural autoimmunity in human health and disease.”. Pathophysiology 19 (3): 221–31.


You will also like...

dinosaurs
The Dinosaurs

Dinosaurs represented a major turn in the evolutionary development of organisms on Earth. The first dinosaurs were presu..

Growth Patterns
Growth Patterns

This tutorial describes the sigmoid curve, annual plant growth, tree growth, human growth, and insect growth as the grow..

A chart depicting Mendel's Law of Dominance
Mendel’s Law & Mendelian Genetics

One of Mendel’s law of inheritance is the “law of dominance”. Read this tutorial to know more about this form of i..

Human Reproduction
Human Reproduction

Humans are capable of only one mode of reproduction, i.e. sexual reproduction. Haploid sex cells (gametes) are produced ..

sponge
Primitive Animals

Life, as we know it today, is presumed to have started in the sea and many of them were likely eukaryotic animal-like or..

Freshwater Ecology
Freshwater Ecology

Freshwater ecology focuses on the relations of aquatic organisms to their freshwater habitats. There are two forms of co..