Dictionary > Avidity

Avidity

Definition
noun, plural: avidities
The combined strength of bond affinities in a complex.
Usage
The term may be used in chemistry to describe the dissociation-dependent strength of an acid or base. In proteins, avidity describes the binding intensity of multiple bond interactions between proteins.
In immunology, avidity refers to the strength of antibodyantigen binding. In this regard, avidity may be different from affinity. The latter being a term used to describe the strength of a particular bond, i.e. the affinity of an antibody for the antigen as the strength of a non-covalent association between an antigen-binding site with a single antigenic epitope1. For instance, IgM may have low affinity but it has high avidity due to its 10 weak binding sites contrary to the two strong binding sites of IgG.
Miscellaneous
Compare: affinity
See also: antibody-antigen complex, protein
Reference:
1Mak, Tak W. and Mary E. Saunders. Primer to the Immune Response. Amsterdam: Academic/Elsevier, 2008. 74.


You will also like...

Kidneys
Kidneys and Regulation of Water and Inorganic Ions

The kidneys are responsible for the regulation of water and inorganic ions. Read this tutorial to learn about the differ..

sponge
Primitive Animals

Life, as we know it today, is presumed to have started in the sea and many of them were likely eukaryotic animal-like or..

running freshwater community
Running Water Freshwater Community Factors

This tutorial noted some of the physical and chemical factors that provide the framework of a running water community in..

Human Nervous System
The Human Nervous System

The nervous system is essentially a biological information highway. This tutorial gives an overview of the nervous syste..

Plant Auxins
Plant Auxins – Phototropism & Geotropism

Plants produce hormones to regulate their growth. Auxins, for instance, influence plant growth. Know the role of auxin i..

3D rendering of an antibody
Passive and Active Types of Immunity

Lymphocytes are a type of white blood cell capable of producing a specific immune response to unique antigens. In thi..

Related Articles...

No related articles found

See all Related Topics