Definition
noun, plural: avidities
The combined strength of bond affinities in a complex.
Usage
The term may be used in chemistry to describe the dissociation-dependent strength of an acid or base. In proteins, avidity describes the binding intensity of multiple bond interactions between proteins.
In immunology, avidity refers to the strength of antibody–antigen binding. In this regard, avidity may be different from affinity. The latter being a term used to describe the strength of a particular bond, i.e. the affinity of an antibody for the antigen as the strength of a non-covalent association between an antigen-binding site with a single antigenic epitope1. For instance, IgM may have low affinity but it has high avidity due to its 10 weak binding sites contrary to the two strong binding sites of IgG.
Miscellaneous
Compare: affinity
See also: antibody-antigen complex, protein
Reference:
1Mak, Tak W. and Mary E. Saunders. Primer to the Immune Response. Amsterdam: Academic/Elsevier, 2008. 74.
Dictionary > Avidity
You will also like...
IQ, Creativity and Learning
Human intelligence provided the means to utilize abstract ideas and implement reasoning. This tutorial takes a further l..
Human Reproduction and Fertilization
For human species to obviate extinction, reproductive mature adults should be producing viable offspring in order to con..
Growth and Development of a Human Baby
Upon fertilization, a zygote forms and develops into an embryo. This tutorial elaborates on the growth and development f..
A Balanced Vitamin Diet – Vitamins A – K
A balanced diet is essential to a healthy organism. Insufficiency or too much of a particular element or compound, such ..
Birth of a Human Baby
Following nine months inside the mother's womb is the birth of the baby. Know the different stages of the birthing proce..
New Zealand’s Biodiversity
Find out more about New Zealand's unique biodiversity by exploring a range of different ecosystems and the key role of s..