Dictionary > Basic dye

Basic dye

Definition
noun, plural: basic dyes
(biological techniques) A dye that ionize in solution giving a positively-charged ions and is used to produce a brilliant color during staining of biological specimen
Supplement
Biological staining is a common laboratory technique applied in the study and identification of a specimen. It is carried out for use in microscopy. An unstained specimen would be difficult to observe in a typical microscope. Staining or dyeing the specimen helps in highlighting microscopic structures such as cell organelles, cells and tissues. There are different kinds of staining techniques. Examples include gram staining, endospore staining, counterstaining, differential staining, Ziehl-Neelsen stain, Haematoxylin and eosin (H&E) staining, Papanicolaou staining, PAS staining, Masson’s trichrome, Romanowsky stains, silver staining, Sudan staining, and Conklin’s staining. Dyes that are used for biological staining may be basic, neutral, or acid.
Basic dyes used in biological staining ionize in solution to give cations (positively charged ions). The cation in a basic dye is the colored component of the dye molecule that binds to anionic groups of nucleic acids or acidic mucopolysaccharides. Basic dyes stain basophilic structures such as nuclei, ribosomes and GAGs. Examples of basic dyes are methylene blue, toluidine blue, thionine, and crystal violet.
Synonym(s):

  • basic stain

Compare:

  • acid dye
  • neutral stain
  • See also:

    Mentioned in:

  • Basoplasm
  • Neutrophilous
  • Basophil adenoma


  • You will also like...

    DNA - schematic
    Genetic Mutations

    This tutorial looks at the mutation at the gene level and the harm it may bring. Learn about single nucleotide polymorph..

    Plant Auxins
    Plant Auxins – Phototropism & Geotropism

    Plants produce hormones to regulate their growth. Auxins, for instance, influence plant growth. Know the role of auxin i..

    Circulation
    Circulation

    The circulatory system is key to the transport of vital biomolecules and nutrients throughout the body. Learn about the ..

    Sigmund Freud and Carl Gustav Jung
    Sigmund Freud and Carl Gustav Jung

    In this tutorial, the works of Carl Gustav Jung and Sigmund Freud are described. Both of them actively pursued the way h..

    kinesin motor proteins transporting molecules across microtubules
    Movement of Molecules Across Cell Membranes

    Molecules move within the cell or from one cell to another through different strategies. Transport may be in the form of..

    Structural depiction of catalase, an enzyme
    Protein Activity and Cellular Metabolism

    Proteins have a crucial role in various biological activities. Get to know how proteins are able to perform as enzymes, ..

    Related Articles...

    No related articles found

    See all Related Topics