Dictionary > Extrinsic pathway

Extrinsic pathway

Definition
noun
(1) (hematology) One of the two initial pathways for the conversion of the prothrombin to thrombin in the coagulation cascade of hemostasis. The pathway is initiated by a trauma to the vascular wall or a trauma to extra-vascular tissues.
(2) (cell biology) One of the two apoptotic pathways identified by bypassing the mitochondria, direct activation of caspases, and the binding of extracellular ligands to initiate specific pro-apoptotic receptors on the cell surface.
Supplement
Word origin: Latin extrinsecus (from without, without, on the outside)
Synonym(s):

  • tissue factor pathway (hematology)

Compare:

  • intrinsic pathway


    You will also like...

    Buttress roots
    Roots

    This study guide tackles plant roots in greater detail. It delves into the development of plant roots, the root structur..

    human brain structure
    The Conscious & Unconscious Nervous System

    This tutorial elaborates on how the nervous system works, particularly at the tissue level of the brain. There are three..

    Chemical effects on plant growth and development
    Effect of Chemicals on Growth & Development in Organisms

    Plants and animals need elements, such as nitrogen, phosphorus, potassium, and magnesium for proper growth and developme..

    Hominid
    The Hominids

    The hominid family diversified from the apes around 6 to 8 million years ago. Since then, the evolutionary path has prov..

    Geological Periods
    Geological Periods

    Geological periods is a study guide that cites the different geological periods on Earth's timeline. Each has a brief ov..

    Homeostatic Mechanisms and Cellular Communication
    Homeostatic Mechanisms and Cellular Communication

    Homeostasis is the relatively stable conditions of the internal environment that result from compensatory regulatory res..