Dictionary > Follicle-stimulating hormone

Follicle-stimulating hormone

noun, plural: follicle-stimulating hormones
A gonadotropin released by the gonadotropes of the anterior pituitary, and responsible for the regulation of the development, growth, pubertal maturation and reproductive processes
Follicle-stimulating hormone is a gonadotropin produced and released by the gonadotropic cells. The gonadotropic cells are one of the many endocrine cell types in the anterior pituitary. Apart from this hormone, these cells release luteinizing hormone (LH) as well.
Follicle-stimulating hormone (FSH) is an acidic glycoprotein hormone made up of two polypeptide units: alpha and beta whereas the glycan subunit is N-acetylgalactosmine, mannose, N-acetylglucosamine, galactose, and sialic acid. This glycan portion of the hormone bonds covalently with asparagine. The polypeptide and the glycan components are essential for FSH to function. It works in synergy with LH. In general, FSH is responsible for the regulation of the development, growth, pubertal maturation and reproductive processes.
In women, FSH stimulates the development of ovarian follicles (eggs) and stimulates the release of oestrogens. In men, FSH stimulates the production of sperm. It induces the Sertoli cells to secrete androgen-binding proteins.
Abnormal FSH levels may be seen in the following conditions: hypopituitarism, Klinefelter syndrome, polycystic ovary disease, Turners syndrome and ovarian failure.
Abbreviation / Acronym:

  • FSH


  • follitropin
  • See also:

    Related term(s):

  • Follicle-stimulating hormone-releasing factor
  • Follicle-stimulating hormone-releasing hormone

    You will also like...

    The Human Physiology
    The Human Physiology

    Physiology is the study of how living organisms function. Thus, human physiology deals specifically with the physiologic..

    Freshwater Ecology
    Freshwater Ecology

    Freshwater ecology focuses on the relations of aquatic organisms to their freshwater habitats. There are two forms of co..

    Gene Regulation in Eukaryotes
    Gene Regulation in Eukaryotes

    Learn about the general structure of a eukaryotic gene, the transcription factors, and post-transcriptional regulation....

    Oligodendrocyte and Schwann cell
    The Central Nervous System

    Myelin sheath is essential for a faster conductivity of signals. Know more about this feature of some neurons in the Cen..

    Ecosystem Succession
    Ecosystem Succession

    If the balance of nature is left untouched, landscapes can change dramatically over time. A previous ecosystem is supers..

    Pink Lotus plant on a pond
    Freshwater Lentic Communities & Animals

    This tutorial looks at some of the communities in freshwater lentic habitats. For instance, symbiosis occurs in a commun..