Dictionary > Inhibitory postsynaptic potential

Inhibitory postsynaptic potential

Inhibitory postsynaptic potential is a type of postsynaptic potential where the binding of neurotransmitters with the postsynaptic receptors causes the opening of ion channels which results in hyperpolarization (or the net gain of negative charge across the membrane) thus the firing of an action potential from the postsynaptic cell is less likely. In general, the resting potential of a neuron is about -70mV and the firing threshold of an action potential is about -50mV. When there is a net gain of negative charge across the membrane of a postsynaptic neuron, the potential moves further to zero or away from the firing threshold. Hence, the postsynaptic potential is inhibitory since the probability to fire an action potential is reduced. Abbreviation: IPSP.

See also


© Biology Online. Content provided and moderated by Biology Online Editors



You will also like...

kinesin motor proteins transporting molecules across microtubules
Movement of Molecules Across Cell Membranes

Molecules move within the cell or from one cell to another through different strategies. Transport may be in the form of..

Schematic diagram of DNA replication
DNA Structure & DNA Replication

DNA is a double helix structure comprised of nucleotides. A nucleotide, in turn, is made up of phosphate molecule, deoxy..

Wart-like leaf galls on grape leaves
Plant Cell Defense

Plants protect themselves by releasing hydrogen peroxide to fight against fungal invasion. Another way is by secreting c..

"Cronopio dentiacutus", a prehistoric mammal (an illustration)
Mammalian Ancestors

Mammals are a diverse group of organisms, where most of them develop their offspring within the uterus of the mother. Ov..

A sperm cell fertilizing an ovum
Human Reproduction and Fertilization

For human species to obviate extinction, reproductive mature adults should be producing viable offspring in order to con..

Pollution in Freshwater Ecosystems
Pollution in Freshwater Ecosystems

There are many environmental factors that arise due to the usage of water in one way or another and for every action tha..