Dictionary > Initiation

Initiation

Definition
noun
(general) The beginning of a state or of a process; the act of initiating
Supplement
In general sense, the term initiation pertains to the beginning of a state or of a process. In biology, the term may be applied to the start of a biological process. For instance, translation, a step in protein biosynthesis wherein the genetic code carried by mRNA is decoded to produce the specific sequence of amino acids in a polypeptide chain, begins when a small subunit of the ribosome binds to the 5′ end of mRNA with the help of initiation factors. This step is referred to as initiation. Nevertheless, prior to initiation, the process of translation would proceed or start when the correct amino acid binds to the correct tRNA, a process called activation. Following initiation, the next step would be elongation (i.e. when the next aminoacyl-tRNA in line binds to the ribosome along with GTP and an elongation factor) and ends with termination (i.e. when the A site of the ribosome encounters a stop codon). Initiation is also the first step in the process of gene transcription, the process of transcribing or making a copy of genetic information stored in a DNA strand into a complementary strand of mRNA.
Related term(s):


You will also like...

Freshwater aquatic plankton
Freshwater Communities & Plankton

Planktons are microscopic organisms that live suspended in aquatic habitats. There are two groups: the phytoplanktons an..

Schematic diagram of bacterial lactose operon
Gene Action – Operon Hypothesis

Learn how the way genes control and determine every aspect of the body. This lesson uses lac operon as an example. ..

..

primitive arthropods
Arthropods

The arthropods were assumed to be the first taxon of species to possess jointed limbs and exoskeleton, exhibit more adva..

Neural Control Mechanisms
Neural Control Mechanisms

Neurons generate electric signals that they pass along to the other neurons or target tissues. In this tutorial, you wil..

mRNA
Protein Synthesis

Part of the genetic information is devoted to the synthesis of proteins. mRNA, a type of RNA, is produced as a transcri..

DNA carries genes coding for proteins
Genetic Information and Protein Synthesis

Genes are expressed through the process of protein synthesis. This elaborate tutorial provides an in-depth review of the..