Dictionary > Monogene

Monogene

Definition
noun, plural: monogenes
(genetics) Single gene controlling the expression of a particular trait
Supplement
In genetics, the term monogene refers to the single gene involved in the expression of a trait. This is in contrast to the polygene, which is a group of genes producing a specific phenotype or trait only when expressed together. The related form monogenic is a descriptive word that relates to a single gene or allele. Terms that are derived from this word are monogenic inheritance and monogenic disorder. In particular, monogenic inheritance is a form of inheritance where a dominant allele influences the complete trait. It is in contrast to the polygenic inheritance where multiple genes are expressed for a particular trait. A monogenic disease is an inherited disease determined by the interaction of a single pair of genes. This is in contrast to a polygenic condition wherein several genes (polygene) are involved. In humans, the monogenic disease is less frequent than the polygenic disease. It is also less complicated than the latter and may follow a pattern based on Mendelian inheritance. Since monogenic disease involves a single pair of genes the dysfunctional or mutated gene may be identified more easily than polygenic disease.
Word origin: monos (one) + gene
See also:

Related form(s):

  • monogenic (adjective, of, or relating to, monogene)


  • You will also like...

    kinesin motor proteins transporting molecules across microtubules
    Movement of Molecules Across Cell Membranes

    Molecules move within the cell or from one cell to another through different strategies. Transport may be in the form of..

    Biological Cell Defense
    Biological Cell Defense

    Organisms employ different strategies to boost its defenses against antigens. Humans have an immune system to combat pat..

    Early Earth
    The Origins of Life

    This tutorial digs into the past to investigate the origins of life. The section is split into geological periods in the..

    river
    Running Water Freshwater Communities

    This tutorial introduces flowing water communities, which bring new and dithering factors into the equation for possible..

    Still Water Community Plants
    Still Water Community Plants

    This tutorial looks at the adaptations of freshwater plants for them to thrive in still water habitats. Familiarize your..

    Water Cycle
    The Water Cycle

    The water cycle (also referred to as the hydrological cycle) is a system of continuous transfer of water from the air, s..

    Related Articles...

    No related articles found

    See all Related Topics