Dictionary > Progestogen

Progestogen

Definition
noun, plural: progestogens
A steroid hormone that is activated by the binding to the progesterone receptor, and whose function is primarily pregnancy maintenance and the preparation of mammary glands for lactation after giving birth
Supplement
Progestogen is one of the major classes of sex steroids (or sex hormones) of vertebrates, including humans. Other sex steroids include androgens and estrogens. Progestogen derived its name from progestational based on one of its main functions, which is pregnancy maintenance. Nevertheless, progestogens are present as well during estrous and menstrual cycle.
Progestogens have a basic 21-carbon structure referred to as pregnane, as opposed to other sex steroids such as estrane (basic 18-carbon structure) in estrogens and androstane (basic 19-carbon structure) in androgens.
Other endogenous progestogens are 16α-hydroxyprogesterone, 17α-hydroxyprogesterone, 20α- and 20β- dihydroprogesterone, 5α- and 5β-dihydroprogesterone, etc. These are important metabolites of progesterone.
Progesterone is an example of progestogen. It is a natural progestogen that is synthesized in the corpus luteum. It acts as an antagonist of estrogens. Its function is to promote the proliferation of uterine mucosa and the implantation of blastocyst. It is also prevents further follicular development.
Progestogens can be produced synthetically and be used as a medication for gynecological disorders. It is also used as an oral contraceptive. Progestin is a synthetic progestogen.
Variant(s):

  • progestagen

Also called:

  • gestagen
  • See also:


    You will also like...

    Human Neurology
    Human Neurology

    Human Neurology deals essentially with the nervous system of humans. It also features the various theories put forward b..

    Digestion and Absorption of Food
    Digestion and Absorption of Food

    The gastrointestinal system breaks down particles of ingested food into molecular forms by enzymes through digestion and..

    Golgi apparatus (3-D illustration)
    Role of Golgi Apparatus & Endoplasmic Reticulum in Protein Synthesis

    The endoplasmic reticulum and Golgi apparatus are the organelles involved in the translation step of protein synthesis a..

    complete-dominance
    Dominance

    This tutorial presents Gregor Mendel's law of dominance. Learn more about this form of inheritance and how it can be pre..

    Kidneys
    Kidneys and Regulation of Water and Inorganic Ions

    The kidneys are responsible for the regulation of water and inorganic ions. Read this tutorial to learn about the differ..

    Geological Periods
    Geological Periods

    Geological periods is a study guide that cites the different geological periods on Earth's timeline. Each has a brief ov..