Dictionary > Rachischisis

Rachischisis

Definition
noun
The embryological failure of the neural tube to fuse or close completely thereby resulting in the vertebrae overlying the open portion of the spinal cord not to fuse and remain open leaving the spinal cord exposed
Supplement
Rachischisis is a developemental birth defect. The posterior neuropore of the neural tube of the developing embryo in the uterus failed to close completely. Rachischisis may affect anywhere along the vertebral axis; it may also affect the entire spine.1
Rachischisis is found to occur commonly with cranial neural tube defects such as anencephaly, acrania, iniencephaly, and myelomeningocele.
Rachischisis is a form of spina bifida, which is a defect during embryological development characterized by an incomplete closing of the backbone and membranes surrounding the spinal cord. Two major types of spina bifida include the spina bifida occulta and the spina bifida cystica. Rachischisis is a subtype of spina bifida cystica together with the other subtypes such as meningocele and myelomeningocele. Rachischisis is described to be the most severe form among the three subtypes.2
Word origin: Greek rachis (spine) + schizein (to split)
Synonym(s):

  • myeloschisis
  • spinal dysraphism
  • spondyloschisis
  • cleft spine

See also:

  • Iniencephaly
  • Derencephaly
  • Derencephalia
  • Spina bifida
  • Cranioschisis
  • Related term(s):

    • Rachischisis partialis
    • Rachischisis totalis

    Reference(s):

    1 Özek, M., Cinalli, G. & Maixner, W. (2008). Spina bifida management and outcome. Milan New York: Springer.

    2 Kavanagh, S. and Tidy, C. (2014). Spina Bifida. Retrieved from http://www.patient.co.uk/doctor/spina-bifida-pro


    You will also like...

    Cell structure
    Cell Structure

    A typical eukaryotic cell is comprised of cytoplasm with different organelles, such as nucleus, endoplasmic reticulum, G..

    Birth Control and Contraception
    Birth Control and Contraception

    Different pregnancy and birth control and contraception strategies are described. Read this tutorial to learn each of th..

    Lake Wakatipu, New Zealand
    New Zealand’s Unique Geographical History

    Explore why New Zealand has such unique flora and fauna, and learn why long periods of geographical isolation. This less..

    Gene Regulation in Eukaryotes
    Gene Regulation in Eukaryotes

    Learn about the general structure of a eukaryotic gene, the transcription factors, and post-transcriptional regulation....

    Homo Species
    The Homo Species

    The evolution of the species of the genus "Homo" led to the emergence of modern humans. Find out more about human evolut..

    Principles of Hormonal Control Systems
    Principles of Hormonal Control Systems

    Hormones are essential in the regulation of the activity of the various biological systems of the human body. The ineffi..

    Related Articles...

    No related articles found

    See all Related Topics